Lamy [28] reported normal level of apelin-12 in the healthy population as 1.11 ng/ml. The literature data about apelin levels in patients with ESRD is limited, so there is no cut-off value for it. But studies reported lower values in dialysis patients compared with the general population [24]. Apelin level was found to be lower in uremic patients with dilated cardiomyopathy than in nonuremic count